منابع مشابه
Leprosy and the human genome.
Despite the availability of effective treatment for several decades, leprosy remains an important medical problem in many regions of the world. Infection with Mycobacterium leprae can produce paucibacillary disease, characterized by well-formed granulomas and a Th1 T-cell response, or multibacillary disease, characterized by poorly organized cellular infiltrates and Th2 cytokines. These diametr...
متن کاملidentification and discovery of novel micrornas in the human genome
although more than 98% of the human genome is transcribed, most of these transcripts are not translated into proteins. rather, they are considered as non-coding rnas. micrornas (mirnas) are very short non-coding rnas approximately 22 nucleotides in length which regulate many key processes of cells such as growth, proliferation, differentiation, cell cycle, apoptosis (programmed cell death) and ...
متن کاملThe Relationship of Human Leprosy and Rat Leprosy
Rat leprosy exhibits certain pathological, bacteriological and clinical features in common with leprosy of man. The delicate rodlike morphology of the bacilli of Stefansky (26) and of Hansen (9), their strongly acid-fast and alcohol-fast staining reactions, and their resistance to cultivation on artificial mediums indicate a close relationship of these two generally accepted etiological agents....
متن کاملLeprosy and human rights.
On the 18th June the United Nations Human Rights Council unanimously adopted a resolution (A/HRC/8/L.18) on ‘The elimination of discrimination against persons affected by leprosy and their family members.’ This historic resolution was sponsored by 59 member states and made specific reference to key earlier documents, namely the Universal of Declaration of Human Rights (1948) and the Internation...
متن کاملThe microbial physiologist's guide to the leprosy genome.
One of the most exciting things about living in the genome sequencing era is that hitherto intractable pathogens can be understood for the first time in unimaginable detail . Many bacterial genomes have been sequenced and one can now enquire about their physiology. 1t is possible not just to enquire about Mycobacterium leprae, but make comparisons with other host-dependent and axenicalIy uncult...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2010
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.00025-10